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Scanning Electron Microscope
Students can examine the finest details at the surface of biological specimens using the Zeiss Evo Scanning Electron Microscope. Here Milan is steering and tilting the electron gun to study the proboscis and protuding tongue. Milan collected this Derbid beetle during her Oxy summer research experience in Costa Rica. Here she is discussing the fine details of the proboscis that identify distinct Derbid species with Prof. Shana Goffredi.
Confocal Fluorescence Microscope
The latest microscope to be purchased in the center is Leica's Stellaris Confocal microscope. Fluorescent labeling of proteins with differently colored markers allows students to detect interactions in biological systems. Here Mikatrain is studying symbiotic interactions in a deep sea sponge sample collected by Prof. Goffredi.
Widefield Microscope
Our Leica Widefield Microscope can quickly acquire multi-colored images of large biological specimens by tiling and stitching images together. Here Prof. North is measuring cell sizes of orchid roots (left image) and Prof. Macabenta is studying larval fly cell migration patterns during development (right image).
Computation
The center houses advanced computational resources. Our newest computer (shared with Joel Walsh in CS) has an NVIDIA RTX Pro 5000 GPU with 48 GB Ram. Here Prof. Alyssa Rodriguez explains here work using Alphafold to identify the 3-dimensional structure of newly discovered proteins. This new computer acquisition gives students access to the most advanced computational methods using the latest developments of AI models in biology, including calculating protein structure using Alphafold, detecting behavior with SLEAP/DeepLabCut. New efforts are focused on trained models installed in computers in the wild that will begin recordings only when a particular species of animal is detected, saving hundreds of hours of still video footage from being collected.
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